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KMID : 0376219810180020309
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Chonnam Medical Journal
1981 Volume.18 No. 2 p.309 ~ p.319
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A Study of Candidiasis in Infants and Mothers
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Abstract
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Candida albicans, which exists most commonly as a normal inhabitant of man on the mucous membrane of the oral cavity, vagina, and in the intestines, can cause opportunistic infection when environmental or host resistance factors become abnormal. Moreover, the population of the candida organism in the oral mucosa and intestines of neonates of infants is higher than that of older children or adults, and accordingly the clinical incidence of oral thrush and cutaneous candidiasis is higher as well.
There are many opinions concerning the transmission and source of such candidiasis, though the most widely believed is that the mother´s vaginal candidiasis is the prime source of infantile candidiasis, and newborn babies may acquire the infection via passage through the infected birth canal. However, the organism, which increases in number during pregnancy, can be transmitted from the mother´s vagina via the birth canal in spite of the absence of any clinical manifestation or history of vaginal candidiasis.
The present study attempts to delineate the relationship of the organism in infants and mothers. The results obtained were as follows:
1. The positive culture rate in the oral cavity and anus of 120 newborn infants was 23% and 53% respectively, and that of premature infants(55%, 75%) was higher than that of normal-term infants(12 % , 38%).
2. The positive culture rate in the vaginal mucosa of 50 healthy nonpregnant females was 22%, and that of 120 pregnant mothers was 41.7%, showing higher incidence in pregnancy.
3. The positive culture rate in the vagina of cases who were positive in the mouth and anus was 60.9% and 51.8%, and that of cases who were positive both in the mouth and anus was 75%.
4. The positive culture rate in the vagina of mothers whose infants had clinically manifested cutaneous candidiasis or oral thrush was 69.4%.
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KEYWORD
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